Milk production in the post-genomic era

Authors

  • Polona FRAJMAN Univ. of Ljubljana, Biotechnical Fac., Dept. of Animal Science, Groblje 3, SI-1230 Domžale, Slovenia
  • Peter DOVČ Univ. of Ljubljana, Biotechnical Fac., Dept. of Animal Science, Groblje 3, SI-1230 Domžale, Slovenia

DOI:

https://doi.org/10.14720/aas.2004.84.2.14745

Keywords:

milk production, technological properties, lactoproteins, molecular genetics, quantitative trait loci, QTL, genomics, micro array

Abstract

Milk plays an important role in human nutrition. Nowadays, dairy industry is oriented in the production of increasing number of different milk products and technological properties of milk are gaining more and more attention. Introduction of recombinant DNA technology in the early 1970 and development of molecular genetics enabled studies of the organization of milk protein genes and mechanisms involved in their expression. Genome research in farm animals was oriented in production of low-density genetic maps with the emphasis on the genetic variation in some functionally important regions. In the public databases, 1598 cattle genes have already been mapped and partially sequenced by the end of 2003. In addition, numerous quantitative trait loci (QTL) were mapped for economically important traits. Typical examples include milk yield and milk composition in dairy cattle. The availability of genomic DNA sequences for a number of potential candidate genes with an impact on production traits allowed construction of cattle genome microarrays. Functional studies of milk protein genes revealed the impact of different genetic variants on technological properties of milk. Genomics approach thus offers an entirely new way to identify complex interactions among milk protein genes other genes involved in milk production and elucidation of the complex regulatory network allowing efficient milk production in the mammary gland.

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Published

20. 12. 2004

Issue

Section

Review Article

How to Cite

FRAJMAN, P., & DOVČ, P. (2004). Milk production in the post-genomic era. Acta Agriculturae Slovenica, 84(2), 109–119. https://doi.org/10.14720/aas.2004.84.2.14745

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