Plant disease resistance genes


  • Petra KOZJAK Agricultural Institute of Slovenia, Hacquetova 17, SI-1000 Ljubljana, Slovenia
  • Branka JAVORNIK Univerza v Ljubljani, Biotehniška fakulteta, Katedra za genetiko, biotehnologijo in žlahtnjenje rastlin, Jamnikarjeva 101, 1000 Ljubljana, Slovenija



disease resistance genes, NBS-LRR genes, plant disease resistance


Plants defend themselves against pathogens using different mechanisms, some of which rely on the expression of disease resistance genes (R genes). R genes encode proteins (R proteins) that provide resistance to a wide spectrum of pathogens including viruses, bacteria, nematodes and fungi. Most of the isolated R genes code for the protein of NBS-LRR class with characteristic nucleotide binding domain (NBS domain) and leucine-rich domain (LRR domain). Models of defence mechanism initiated by R gene products are proposed, based either on direct or indirect interaction of the plant R protein with the product of avirulence pathogen gene. Most of the R gene and R gene-like sequences are isolated by insertional mutagenesis, map-based cloning and amplification by polymerase chain reaction (PCR).


15. 05. 2008



Review Article

How to Cite

KOZJAK, P., & JAVORNIK, B. (2008). Plant disease resistance genes. Acta Agriculturae Slovenica, 91(1), 139–156.

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