Environmental alterations on potency of eugenol content of basil: an antihypertensive herb
DOI:
https://doi.org/10.14720/abs.67.1.18390Keywords:
Alkaloids, Environment, Fluctuations, Herbal therapy, IdentificationAbstract
Herbal therapies demand increases worldwide for treatment of various diseases. About 75% to 80% of the world population use herbal medicines, mainly in developing countries, for primary health care because of their better acceptability with the human body and lesser side effects. Herbal medicines are used for treatment of such a chronic diseases from hundreds of years and are continuously rising in today’s era due to less adverse effects, treats root cause and low cost. Medicinal plants are used to treat patients with cardiovascular diseases, which may occur due to ailments of the heart and blood vessels and comprise heart attacks, cerebrovascular diseases, hypertension, and heart failure. Research has found a variety of herbal therapies to be successful in reducing high blood pressure with diet, exercise, stress management and supplements. Environmental changes have impact on availability of herbal constituents along with its therapeutic efficacy. If harvesting should be done properly at accurate conditions gets yield with more potency. Plant sample used in different seasons, time and places, identification and analysis was performed. Morphological, microscopical and extractive values appear changes. Maximum levels of ethanol extract with higher concentration of eugenol were obtained in rainy season, at high altitude and at morning time.
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Dieniffer Peixoto-Neves , Jose Henrique Leal-Cardoso, Jonathan H Jaggar 2014. Eugenol dilates rat cerebral arteries by inhibiting smooth muscle cell voltage-dependent calcium channels. J. Cardiovasc. Pharmacol. 64 (5): 401-6. doi: 10.1097/FJC.0000000000000131).
Nahida Tabassum, Feroz Ahmad 2011. Role of natural herbs in the treatment of hypertension. Pharmacogn Rev. Jan; 5(9):30-40. doi: 10.4103/0973-7847.79097
Anwar Umar, Guzelnur Imam, Wuliya Yimin, Parhat Kerim, Ibadet Tohti, Benedicte Berke, Nicholas Moore 2010. Antihypertensive effects of Ocimum basilicum L. (OBL) on blood pressure in renovascular hypertensive rats. Hypertens. Res. Jul;33(7):727-30. doi: 10.1038/hr.2010.64. ).
Souliman Amrani , Hicham Harnafi, Dounia Gadi, Hassane Mekhfi, Abdelkhaleq Legssyer, Mohammed Aziz, Francoise Martin-Nizard, Lisardo Bosca 2009. Vasorelaxant and anti-platelet aggregation effects of aqueous Ocimum basilicum extract J Ethnopharmacol. Aug 17;125(1):157-62. doi: 10.1016/j.jep.2009.05.043.
Al Disi SS, Anwar MA, Eid AH. 2015. Anti-hypertensive herbs and their mechanisms of action: part I. Front Pharmacol. ;6:323. doi: 10.3389/fphar.2015.00323.
Wang J, Xiong X. 2012. Control strategy on hypertension in Chinese medicine. Evid Based Complement Alternat Med. ;2012:284847. doi: 10.1155/2012/284847.
Anwar MA, Al Disi SS, Eid AH. 2016. Anti-hypertensive herbs and their mechanisms of action: part II. Front Pharmacol. ;7:50. doi: 10.3389/fphar.2016.00050.
Hashemi V, Dolati S, Hosseini A, Gharibi T, Danaii S, Yousefi M. 2017. Natural killer T cells in preeclampsia: an updated review. Biomed Pharmacother. ;95:412–8. doi: 10.1016/j.biopha.2017.08.077.
Sinha AD, Agarwal R. 2019. Clinical pharmacology of antihypertensive therapy for the treatment of hypertension in CKD. Clin J Am Soc Nephrol. ;14(5):757–64. doi: 10.2215/cjn.04330418.
Singh P, Mishra A, Singh P, Goswami S, Singh A, Tiwari KD. 2015. Hypertension and herbal plant for its treatment: a review. Indian J Res Pharm Biotechnol. ;3(5):358–66.
Rastogi S, Pandey MM, Rawat AK. 2016. Traditional herbs: a remedy for cardiovascular disorders. Phytomedicine. ;23(11):1082–9. doi: 10.1016/j.phymed.2015.10.012.
Shayganni E, Bahmani M, Asgary S, Rafieian-Kopaei M. 2016. Inflammaging and cardiovascular disease: management by medicinal plants. Phytomedicine. ;23(11):1119–26. doi: 10.1016/j.phymed.2015.11.004.
Umar A, Imam G, Yimin W, Kerim P, Tohti I, Berke B. et al. 2010. Antihypertensive effects of Ocimum basilicum L (OBL) on blood pressure in renovascular hypertensive rats. Hypertens Res. ;33(7):727–30. doi: 10.1038/hr.2010.64.
Chaudhury A. , Chitharanjan Duvoor, Vijaya Sena Reddy Dendi, Shashank Kraleti, Aditya Chada, Rahul Ravilla, Asween Marco, Nawal Singh Shekhawat, Maria Theresa Montales, Kevin Kuriakose, Appalanaidu Sasapu, Alexandria Beebe, Naveen Patil, Chaitanya K. Musham, Govinda Prasad Lohani and Wasique Mirza 2017. Clinical Review of Antidiabetic Drugs: Implications for Type 2 Diabetes Mellitus Management. Frontiers in Endocrinology 8 (6) doi: 10.3389/fendo.2017.00006 1-12.
Asha Thomas, Abhilash Kanakdhar , Adinath Shirsat, Sanjeevani Deshkar, Lata Kothapalli 2020. A High Performance Thin Layer Chromatographic Method Using a Design of Experiment Approach. Turk J Pharm Sci. 17(2):148-158. DOI: 10.4274/tjps.galenos.2018.80958.
Feneli Karachaliou, George Simatos and Aristofania Simatou 2020. The Challenges in the Development of Diabetes Prevention and Care Models in Low-Income Settings Front. Endocrinol Vol. 11, 518 1-9 doi.org/10.3389/fendo.2020.00518.
Haidan Yuan, Qianqian Ma, Li Ye, Guangchun Piao 2016. The Traditional Medicine and Modern Medicine from Natural Products Molecules. Molecules 21, 559; 1-18. doi: 10.3390/molecules21050559.
Martins Ekor 2013. The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety. Front Pharmacol. 4: 177. doi: 10.3389/fphar.2013.00177.
N H Cho, J E Shaw, S Karuranga, Y Huang, J D da Rocha Fernandes, A W Ohlrogge, B Malanda, 2018. Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045. Diabetes Res Clin Pract 138:271-281 10.1016/j.diabres.2018.02.023.
Ngan Tran, Bao Pham, Ly Le, 2020. Bioactive Compounds in Anti-Diabetic Plants: From Herbal Medicine to Modern Drug Discovery. Biology 9 (9), 252; doi.org/10.3390/biology9090252.
Oyinlola Oyebode, Ngianga-Bakwin Kandala, Peter J Chilton, Richard J Lilford 2016. Use of traditional medicine in middle-income countries: a WHO-SAGE study. Health Policy Plan.31(8): 984–991. doi: 10.1093/heapol/czw022.
Saikat Sen and Raja Chakraborty, 2017. Revival, modernization and integration of Indian traditional herbal medicine in clinical practice: Importance, challenges and future, J Tradit Complement Med. Apr; 7(2): 234–244. doi: 10.1016/j.jtcme.2016.05.006.
Shi-Lin Chen, Hua Yu, Hong-Mei Luo, Qiong Wu, Chun-Fang Li & André Steinmetz 2016. Conservation and sustainable use of medicinal plants: problems, progress, and prospects. Chinese Medicine 11: 37, 1-6. doi: 10.1186/s13020- 016-0108-7.
Sushree Priyanka Dash, Sangita Dixit and Soubhagyalaxmi Sahoo 2017. Phytochemical and Biochemical Characterizations from Leaf Extracts from Azadirachta Indica: An Important Medicinal Plant. Biochemistry & Analytical Biochemistry 6:2, 1-4. DOI: 10.4172/2161-1009.1000323.
Uttpal Anand, Nadia Jacobo Herrera, Ammar Altemimi, Naoufal Lakhssassi 2019. A Comprehensive Review on Medicinal Plants as Antimicrobial Therapeutics: Potential
Avenues of Biocompatible Drug Discovery. Metabolites 9 (11): 258. doi: 10.3390/metabo9110258.
Wesam Kooti, Maryam Farokhipour, Zahra Asadzadeh, Damoon Ashtary-Larky, and Majid Asadi-Samani, 2016. The role of medicinal plants in the treatment of diabetes. Electron Physician 8(1): 1832–1842. doi: 10.19082/1832.
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