The Impact of Diet on Oral Microbiome and Periodontal Health

Authors

  • Tina Robič Zobozdravstvo diamant d.o.o.

DOI:

https://doi.org/10.14720/abs.67.3.19196

Keywords:

Periodontal disease, Nutrients, Diet, Immune response, Oral microbiome, Probiotics

Abstract

Periodontal disease is a chronic inflammatory condition that affects the supporting tissues of the teeth and can lead to tooth loss if not properly treated. The main cause of periodontal disease is an imbalance in the oral microbiome, the complex community of microorganisms inhabiting the oral cavity. Disruption of this balance can lead to the overgrowth of pathogenic bacteria that trigger an inflammatory response in the gums. Diet also has a significant impact on the composition and diversity of the oral microbiome, and thus can greatly influence gum health and overall oral health. Including anti-inflammatory nutrients such as omega-3 fatty acids, antioxidants, vitamin D, polyphenols in the diet and reducing sugar intake can help manage and prevent periodontal disease. The therapeutic use of probiotics, such as bifidobacteria and lactobacilli, represents a new concept in dentistry. Research shows that regular use of probiotic supplements or probiotic-rich foods, such as yogurts and fermented foods, supports the maintenance of a balanced oral microbiome. Probiotics in periodontal disease work by inhibiting the growth of pathogenic bacteria, reducing inflammatory responses in the oral cavity, and stimulating the immune system for better defense against infections. Additionally, they promote the proliferation of fibroblasts, thereby supporting tissue healing. Diet control, intake of vitamin supplements, and probiotics, combined with good oral hygiene and regular dental visits, can significantly improve gum health and prevent the progression of periodontal disease.

Metrics

Metrics Loading ...

References

Abullais, S. S., Patel, S. I., Asiri, E. A., Jathmi, A. A. A., Alkhayri, A. H., Mousa, Y. M., Ganem, A. A., & Mattoo, K. A. (2022). Comparative Evaluation of 3 Commercial Mouthwash Formulations on Clinical Parameters of Chronic Gingivitis. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research, 28, e937111-1-e937111-10. https://doi.org/10.12659/MSM.937111

Alshareef, A., Attia, A., Almalki, M., Alsharif, F., Melibari, A., Mirdad, B., Azab, E., Youssef, A.-R., & Dardir, A. (2020). Effectiveness of Probiotic Lozenges in Periodontal Management of Chronic Periodontitis Patients: Clinical and Immunological Study. European Journal of Dentistry, 14(2), 281–287. https://doi.org/10.1055/s-0040-1709924

Cao, R., Li, A., Geng, F., & Pan, Y. (2024). Associations of dietary antioxidant intake with periodontal health among US adults: An exploratory mediation analysis via mitochondrial function. Journal of Clinical Periodontology, 51(6), 702–711. https://doi.org/10.1111/jcpe.13960

Chandra, R. V., Sandhya, Y. P., Nagarajan, S., Reddy, B. H., Naveen, A., & Murthy, K. R. V. (2012). Efficacy of lycopene as a locally delivered gel in the treatment of chronic periodontitis: Smokers vs nonsmokers. Quintessence International (Berlin, Germany: 1985), 43(5), 401–411.

Chapple, I. L. C., Milward, M. R., & Dietrich, T. (2007). The prevalence of inflammatory periodontitis is negatively associated with serum antioxidant concentrations. The Journal of Nutrition, 137(3), 657–664. https://doi.org/10.1093/jn/137.3.657

Choi, Y., Park, E., Kim, S., Ha, J., Oh, H., Kim, Y., Lee, Y., Seo, Y., Kang, J., Lee, S., Lee, H., Yoon, Y., & Choi, K.-H. (2021). Alleviation of periodontal disease using Lactobacillus curvatus SMFM2016-NK. Journal of Functional Foods, 83, 104531. https://doi.org/10.1016/j.jff.2021.104531

Dommisch, H., Kuzmanova, D., Jönsson, D., Grant, M., & Chapple, I. (2018). Effect of micronutrient malnutrition on periodontal disease and periodontal therapy. Periodontology 2000, 78(1), 129–153. https://doi.org/10.1111/prd.12233

Hujoel, P. P., & Lingström, P. (2017). Nutrition, dental caries and periodontal disease: A narrative review. Journal of Clinical Periodontology, 44 Suppl 18, S79–S84. https://doi.org/10.1111/jcpe.12672

Isola, G., Polizzi, A., Santonocito, S., Alibrandi, A., & Williams, R. C. (2022). Periodontitis activates the NLRP3 inflammasome in serum and saliva. Journal of Periodontology, 93(1), 135–145. https://doi.org/10.1002/JPER.21-0049

Iwasaki, M., Manz, M. C., Moynihan, P., Yoshihara, A., Muramatsu, K., Watanabe, R., & Miyazaki, H. (2011). Relationship between saturated fatty acids and periodontal disease. Journal of Dental Research, 90(7), 861–867. https://doi.org/10.1177/0022034511405384

Kruse, A. B., Kowalski, C. D., Leuthold, S., Vach, K., Ratka-Krüger, P., & Woelber, J. P. (2020). What is the impact of the adjunctive use of omega-3 fatty acids in the treatment of periodontitis? A systematic review and meta-analysis. Lipids in Health and Disease, 19(1), 100. https://doi.org/10.1186/s12944-020-01267-x

Lenartova, M., Tesinska, B., Janatova, T., Hrebicek, O., Mysak, J., Janata, J., & Najmanova, L. (2021). The Oral Microbiome in Periodontal Health. Frontiers in Cellular and Infection Microbiology, 11, 629723. https://doi.org/10.3389/fcimb.2021.629723

McSorley, R. (2024). Multi-nutrients and periodontal disease – a new adjunct to improving treatment outcomes? A randomised placebo-control clinical trial. Evidence-Based Dentistry, 1–2. https://doi.org/10.1038/s41432-024-01010-w

Najeeb, S., Zafar, M. S., Khurshid, Z., Zohaib, S., & Almas, K. (2016). The Role of Nutrition in Periodontal Health: An Update. Nutrients, 8(9), 530. https://doi.org/10.3390/nu8090530

Pack, A. R., & Thomson, M. E. (1980). Effects of topical and systemic folic acid supplementation on gingivitis in pregnancy. Journal of Clinical Periodontology, 7(5), 402–414. https://doi.org/10.1111/j.1600-051x.1980.tb02013.x

Roy, Dr. A., Kalburgi, Dr. N. B., Koregol, Dr. A. C., & Sultana, Dr. U. P. (2024). Probiotics in periodontal therapy: An enigmatic review. International Journal of Applied Dental Sciences, 10(1), 200–205. https://doi.org/10.22271/oral.2024.v10.i1c.1911

Selvaraj, S., & Gurumurthy, K. (2022). An overview of probiotic health booster-kombucha tea. Chinese Herbal Medicines, 15(1), 27–32. https://doi.org/10.1016/j.chmed.2022.06.010

Shah, M., Poojari, M., Nadig, P. R., Kakkad, D., Dutta, S. B., Sinha, S., Chowdhury, K., Dagli, N., Haque, M., & Kumar, S. (2023). Vitamin D and Periodontal Health: A Systematic Review. Cureus. https://doi.org/10.7759/cureus.47773

Shimabukuro, Y., Nakayama, Y., Ogata, Y., Tamazawa, K., Shimauchi, H., Nishida, T., Ito, K., Chikazawa, T., Kataoka, S., & Murakami, S. (2015). Effects of an ascorbic acid-derivative dentifrice in patients with gingivitis: A double-masked, randomized, controlled clinical trial. Journal of Periodontology, 86(1), 27–35. https://doi.org/10.1902/jop.2014.140138

Shimazaki, Y., Shirota, T., Uchida, K., Yonemoto, K., Kiyohara, Y., Iida, M., Saito, T., & Yamashita, Y. (2008). Intake of dairy products and periodontal disease: The Hisayama Study. Journal of Periodontology, 79(1), 131–137. https://doi.org/10.1902/jop.2008.070202

Shirbhate, U., Bajaj, P., Chandak, M., Jaiswal, P., Sarangi, S., Suchak, D., & Bharti, L. (2023). Clinical Implications of Probiotics in Oral and Periodontal Health: A Comprehensive Review. Cureus, 15(12), e51177. https://doi.org/10.7759/cureus.51177

Staudte, H., Sigusch, B. W., & Glockmann, E. (2005). Grapefruit consumption improves vitamin C status in periodontitis patients. British Dental Journal, 199(4), 213–217, discussion 210. https://doi.org/10.1038/sj.bdj.4812613

Teughels, W., Durukan, A., Ozcelik, O., Pauwels, M., Quirynen, M., & Haytac, M. C. (2013). Clinical and microbiological effects of Lactobacillus reuteri probiotics in the treatment of chronic periodontitis: A randomized placebo-controlled study. Journal of Clinical Periodontology, 40(11), 1025–1035. https://doi.org/10.1111/jcpe.12155

Van Ravensteijn, M. M., Timmerman, M. F., Brouwer, E. A. G., & Slot, D. E. (2022). The effect of omega-3 fatty acids on active periodontal therapy: A systematic review and meta-analysis. Journal of Clinical Periodontology, 49(10), 1024–1037. https://doi.org/10.1111/jcpe.13680

Woelber, J. P., & Tennert, C. (2020). Chapter 13: Diet and Periodontal Diseases. Monographs in Oral Science, 28, 125–133. https://doi.org/10.1159/000455380

Zong, G., Holtfreter, B., Scott, A. E., Völzke, H., Petersmann, A., Dietrich, T., Newson, R. S., & Kocher, T. (2016). Serum vitamin B12 is inversely associated with periodontal progression and risk of tooth loss: A prospective cohort study. Journal of Clinical Periodontology, 43(1), 2–9. https://doi.org/10.1111/jcpe.12483

Published

23.08.2024

How to Cite

Robič, T. (2024). The Impact of Diet on Oral Microbiome and Periodontal Health. Acta Biologica Slovenica, 67(3), 70-79. https://doi.org/10.14720/abs.67.3.19196